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Non-Viral Cytokine-Inducible SH2 Containing ProteinLocus-Specific Integrated Fibroblast Activation ProteinAlpha-Targeting Chimeric Antigen Receptor T Cells AchievePotent Antitumor Efficacy in Glioblastoma featuring Full Circles Therapeutics

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ABSTRACT Chimeric antigen receptor T (CAR-T) cells have been used to treat patients with glioblastoma (GBM) in clinical trial settings bytargeting GBM-associated antigens. However, the efficacy of these CAR-T cells remains limited mainly due to the heterogeneousexpression of tumor antigen...
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Real-time intraoperative confocal laser endomicroscopy with on-site neuropathologist consultation for glioma margin assessment: illustrative case featuring VPIX Medical

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This report presents an illustrative case demonstrating a practical collaborative workflow that integrates CLE with on-site neuropathologist consultation for real-time margin assessment during glioma resection. We used the cCeLL-In vivo system (VPIX Medical Inc.), a handheld CLE device with US...
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