Neurent Medical has published results from its RELEASE study in the Ear, Nose & Throat Journal. RELEASE was an exploratory study evaluating impedance-controlled posterior nasal nerve (PNN) radiofrequency ablation as a potential treatment approach for patients with chronic migraine. Outcomes assessed included mean monthly migraine headache days, responder rate (a ≥50% improvement in monthly migraine headache days), headache-related quality of life and safety. Because RELEASE was an exploratory feasibility study with a small sample size and no randomized or sham-controlled comparator, the company notes that additional controlled clinical studies are needed to further evaluate the potential role of PNN ablation in migraine.
Neurent Medical publishes results from its RELEASE study of posterior nasal nerve ablation in chronic migraine
